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KMID : 0388220120190030163
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Journal of the Korean Rheumatism Association
2012 Volume.19 No. 3 p.163 ~ p.167
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A Case of Polyarteritis Nodosa Manifesting as a Neuropathy Following Influenza Infection
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Lee Dong-Hwa
Han Joung-Ho
Kim Mi-Kyoung
Lee Ok-Jun
Kang Kwi-Young
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Abstract
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Polyarteritis nodosa (PAN) is a necrotizing vasculitis of the medium-sized arteries. The symptoms and signs of PAN include purpuric skin lesions, mononeuritis multiplex, symptoms of mesenteric ischemia, and renal involvement. We report the first case of PAN manifesting as a neuropathy after influenza infection in Korea. A 68-year-old woman had fever, myalgia, hyperesthesia of both hand and foot, and lower extremity weakness. EMG findings showed severe sensorimotor polyneuropathy, such as multiple mononeuritis. A sural nerve biopsy showed vasculitis and Influenza A (H1N1) were positive. Our patient was treated by glucocorticoid and oral cyclophosphamide, thereafter, symptoms and signs improved. No recurrence has been observed for five months.
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KEYWORD
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Polyarteritis nodosa, Influenza infection, Neuropathy
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